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TraStuzumAb-Radiotherapy : Impact on the Cerebral Prevention
Sponsor: Centre Oscar Lambret
Summary
Evaluate the survival without metastasis in patients treated by Trastuzumab in association with other chemotherapies for a breast cancer expressing HER2-NEU.
Official title: Interest of the Prophylactic Cerebral Radiotherapy in the Metastatic Breast Cancer Expressing HER2/NEU Treated by Trastuzumab
Key Details
Gender
FEMALE
Age Range
18 Years - 70 Years
Study Type
INTERVENTIONAL
Enrollment
13
Start Date
2008-01
Completion Date
2012-01
Last Updated
2026-09-17
Healthy Volunteers
No
Interventions
cerebral prophylactic radiation
24Gy, 12 fractions of 2 Gy
Trastuzumab
Weekly, 2mg/kg of corporal weight
Other chemotherapy in association with Trastuzumab
other chemotherapy is possible to associate with Trastuzumab as well as a change of chemotherapy protocol is possible while maintening Trastuzumab 8 weeks is required between last injection of chemotherapy and first radiotherapy session
Locations (26)
Centre Paul Papin
Angers, France
Centre Hospitalier
Boulogne-sur-Mer, France
Centre Maurice Tubiana
Caen, France
Centre G-François Baclesse
Caen, France
Centre Léonard de Vinci
Dechy, France
Centre Médical de Forcilles
Forcilles-attilly, France
Clinique des Ormeaux- Vauban
Le Havre, France
Centre Bourgogne
Lille, France
Centre Oscar LAMBRET
Lille, France
CHU Dupuytren
Limoges, France
Clinique Clinique Clementville
Montpellier, France
Centre Azuréen de Cancérologie
Mougins, France
Centre Hospitalier de Mulhouse
Mulhouse, France
Centre Catherine de Sienne
Nantes, France
Clinique Hartmann
Neuilly-sur-Seine, France
Centre Antoine Lacassagne
Nice, France
Centre médical Oncogard
Nîmes, France
Hôpital Tenon
Paris, France
Centre Catalan d'Oncologie
Perpignan, France
Centre Hospitalier LYON SUD
Pierre-Bénite, France
Centre René Huguenin
Saint-Cloud, France
Centre Etienne DOLET
Saint-Nazaire, France
Centre de Cancérologie Paris Nord
Sarcelles, France
Oncorad Garonne
Toulouse, France
Centre Alexis Vautrin
Vandœuvre-lès-Nancy, France
Institut Gustave Roussy
Villejuif, France