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Vitamin D and Omega-3 Hypertension Trial (VITAL Hypertension)
Sponsor: Brigham and Women's Hospital
Summary
The VITamin D and OmegA-3 TriaL (VITAL; NCT 01169259) is an ongoing randomized clinical trial in 25,875 U.S. men and women investigating whether taking daily dietary supplements of vitamin D3 (2000 IU) or omega-3 fatty acids (Omacor® fish oil, 1 gram) reduces the risk of developing cancer, heart disease, and stroke in people who do not have a prior history of these illnesses. The VITAL Hypertension ancillary study is being conducted among participants in VITAL and will examine whether vitamin D or omega-3 fatty acids are related to changes in blood pressure and hypertension.
Official title: Effect of Vitamin D and Omega-3 Fatty Acids on Blood Pressure and Hypertension
Key Details
Gender
All
Age Range
50 Years - 99 Years
Study Type
INTERVENTIONAL
Enrollment
25875
Start Date
2011-11
Completion Date
2026-06
Last Updated
2025-12-18
Healthy Volunteers
Yes
Conditions
Interventions
Vitamin D-3 (cholecalciferol), 2000 IU
Omega-3 fatty acids (fish oil)
Omacor, 1 capsule per day. Each capsule of Omacor contains 840 milligrams of marine omega-3 fatty acids (465 mg of eicosapentaenoic acid \[EPA\] and 375 mg of docosahexaenoic acid \[DHA\])
Vitamin D placebo
Fish oil placebo
Locations (1)
Brigham and Women's Hospital
Boston, Massachusetts, United States