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COsegregation of VARiants in Panel of Genes
Sponsor: Institut Curie
Summary
The aim of the COVAR project is to classify reliably a maximum of VUS of the French database in order to use them for the genetic counseling. The results obtained through this study will have a major impact on clinical management of the patients and their families conducting in some cases to propose a prophylactic surgery.
Official title: Study of Family COsegregation of Nucleotide VARiants in the Panel of Genes to Validate Their Use in Genetic Counseling
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
3500
Start Date
2012-07-02
Completion Date
2034-01-02
Last Updated
2025-04-06
Healthy Volunteers
No
Interventions
salivary kit
The saliva samples will be made of selected related (DNA).
Locations (57)
Institut Curie - Hopital Rene Huguenin
Saint-Cloud, Haut de Seine, France
CHU Amiens - Hôpital Nord
Amiens, France
ICO - Centre Paul Papin
Angers, France
Centre Hospitalier d'Angoulème
Angoulême, France
Institut Sainte-Catherine
Avignon, France
CHU Besançon
Besançon, France
Groupe Hospitalier Pellegrin
Bordeaux, France
Institut Bergonié
Bordeaux, France
Centre Hospitalier Jacques Coeur
Bourges, France
CHU Morvan de Brest
Brest, France
Centre François Baclesse
Caen, France
Centre Hospitalier Hôtel Dieu
Chambéry, France
Centre Jean Perrin
Clermont-Ferrand, France
Hôpital Civil de Colmar
Colmar, France
CHU de Dijon
Dijon, France
CHU de Grenoble
Grenoble, France
Groupe Hospitalier La Rochelle-Ré-Aunis
La Rochelle, France
Hôpital Flaubert
Le Havre, France
Centre Oscar Lambret
Lille, France
Chru Lille
Lille, France
CHU Dupuytren
Limoges, France
Hospices Civils de Lyon
Lyon, France
Centre Léon Bérard
Lyon, France
Institut Paoli Calmettes
Marseille, France
CHU La Timone
Marseille, France
CHU Arnaud de Villeneuve
Montpellier, France
Centre Catherine de Sienne
Nantes, France
Centre Antoine Lacassagne
Nice, France
Centre Hospitalier Georges Renon
Niort, France
CHRU Caremeau
Nîmes, France
Hôpital de la Source
Orléans, France
Hôpital Saint-Antoine
Paris, France
Groupe Hospitalier Pitié-Salpêtrière
Paris, France
Hôpital Tenon
Paris, France
Hôpital Saint-Louis
Paris, France
HEGP
Paris, France
CHU La Milétrie
Poitiers, France
CHU de Reims
Reims, France
ICC Courlancy
Reims, France
Institut Jean Godinot
Reims, France
Centre Eugène Marquis
Rennes, France
CHU de Rouen
Rouen, France
CHU Saint Etienne
Saint-Etienne, France
ICO - Centre René Gauducheau
Saint-Herblain, France
Institut de Cancérologie Strasbourg Europe ICANS
Strasbourg, France
Hopital de Hautepierre - Hôpital Universitaire
Strasbourg, France
Institut Claudius Regaud - IUCT - Oncopole
Toulouse, France
CHU Bretonneau
Tours, France
CH Simone VEIL
Troyes, France
Centre Hospitalier de Valence
Valence, France
Centre Alexis Vautrin
Vandœuvre-lès-Nancy, France
CHU Nancy - Hôpital Brabois
Vandœuvre-lès-Nancy, France
Gustave Roussy
Villejuif, France
Institut Curie
Paris, Île-de-France Region, France
CHU de Pointe à Pitre
Pointe-à-Pitre, Guadeloupe
CHU de Fort de France
Fort-de-France, Martinique
CHU Sud Réunion Saint-Pierre
Saint-Pierre, Reunion