Clinical Research Directory
Browse clinical research sites, groups, and studies.
Autologous Cultured Corneal Epithelium (CECA) for the Treatment of Limbal Stem Cell Deficiency
Sponsor: CHU de Quebec-Universite Laval
Summary
The study " Autologous cultured corneal epithelium (CECA) for the treatment of corneal lesions associated with limbal stem cell deficiency" is the first clinical trial of this product manufactured at the LOEX laboratory. The culture of corneal epithelium strives to produce a reconstructed tissue with the therapeutical aim of treatment of limbal stem cell deficiency. The study is a phase I/phase II study with the goal to evaluate safety and efficacy of the CECA graft for the treatment of human patients suffering from limbal stem cell deficiency. The trial is open to all genders. The inclusion of 5 minors is planned.
Official title: Autologous Cultured Corneal Epithelium ( Culture d'épithélium cornéen Autologue CECA) for the Treatment of Unilateral Corneal Lesions Associated With Limbal Stem Cell Deficiency
Key Details
Gender
All
Age Range
1 Year - Any
Study Type
INTERVENTIONAL
Enrollment
54
Start Date
2012-12
Completion Date
2027-12
Last Updated
2025-07-10
Healthy Volunteers
No
Conditions
Interventions
Surgical transplantation of ACCE
The culture of corneal epithelium strives to produce a reconstructed tissue with the therapeutical aim of treatment of limbal stem cell deficiency.
Locations (4)
University Health Network - Toronto Western Hospital
Toronto, Ontario, Canada
CIUSSS de l'Est de l'île de Montréal
Montreal, Quebec, Canada
McGill University Health Centre; Centre de Médecine Innovatrice/Centre for Innovative Medicine
Montreal, Quebec, Canada
Centre universitaire d'Ophtalmologie CHU de Québec - HSS
Québec, Quebec, Canada