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Effect of Sacral Nerve Stimulation on Enteric Nervous System
Sponsor: University Hospital, Rouen
Summary
Sacral nerve stimulation (SNS) is a new therapeutic option to treat fecal incontinence, although its mecanims of action remains poorly understood. The investigators hypothtized that SNS could act on enteric nervous system (ENS). To verify this hypothesis, the investigators will collect biopsy samples from patients implanted for SNS, and assess whether SNS induces changes in ENS.
Key Details
Gender
All
Age Range
18 Years - 75 Years
Study Type
INTERVENTIONAL
Enrollment
37
Start Date
2013-01
Completion Date
2016-11
Last Updated
2026-06-03
Healthy Volunteers
No
Conditions
Interventions
Sacral nerve stimulation
implantation of a stimulation electrode in one of the S2-S3-S4 sacral hole then connected to a subcutaneous stimulator for permanent stimulation of the sacral nerve
Locations (2)
Rouen University Hospital
Rouen, Normandy, France
Nantes University Hospital
Nantes, Pays de Loire, France