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COMPLETED
NCT01811251
PHASE3

Co-analgesic Effects of Dexamethasone and Pregabalin After Lumbar Slipped Disc Surgery

Sponsor: University Hospital, Clermont-Ferrand

View on ClinicalTrials.gov

Summary

The aim of the study is to show a decrease in postoperative pain during the first postoperative mobilization surgery lumbar disc herniation through a co-analgesia with a single dose of dexamethasone, pregabalin, or a combination of these two products. Pain assessed by simple numerical scale will be also evaluated during the 48 first post-operative hours. Determining an optimal co-analgesic protocol through the results of this study could help develop validation studies with larger scale such as a medico-economic component. In addition, these study protocols are easy to apply (ponctual administration) and inexpensive.

Key Details

Gender

All

Age Range

18 Years - 85 Years

Study Type

INTERVENTIONAL

Enrollment

162

Start Date

2012-12

Completion Date

2017-10-10

Last Updated

2026-08-10

Healthy Volunteers

No

Interventions

DRUG

Pregabaline (150mg), Dexamethasone (20mg/5ml; 0.2mg/kg)

Locations (1)

CHU Clermont-Ferrand

Clermont-Ferrand, France