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The Efficacy and Safety of the Postoperative Adjuvant Treatment in Patients With High-risk Stage I Endometrial Carcinoma
Sponsor: Ding Ma
Summary
This randomized trial is studying the efficacy and safety of the chemotherapy compared with radiation therapy alone as adjuvant treatment after operation in Patients with high risk and Stage I endometrial carcinoma.
Official title: A Multicenter, Prospective, Randomized Trial of the Efficacy and Safety of the Postoperative Adjuvant Treatment in Patients With High-risk Stage I Endometrial Carcinoma
Key Details
Gender
FEMALE
Age Range
18 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
300
Start Date
2012-11
Completion Date
2026-12
Last Updated
2024-04-02
Healthy Volunteers
No
Conditions
Interventions
Paclitaxel
175 mg/m(2), intravenously (IV)
Paraplatin (Carboplatin Injection)
AUC=5, IV
Pelvic Radiation
45-50 Gy
Vaginal Brachytherapy 1
5 Gy, 3 times
Vaginal brachytherapy 2
5 Gy, 2-4 times
Locations (3)
Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
Wuhan, Hubei, China
Qilu Hospital，Shandong University
Jinan, Shandong, China
Women's Hospital, School of Medicine, Zhejiang University
Hangzhou, Zhejiang, China