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COMPLETED
NCT01823263
NA

Metabolic and Cognitive Parameters Following Partial Sleep Deprivation

Sponsor: Uppsala University

View on ClinicalTrials.gov

Summary

The purpose of this study is to determine whether partial sleep deprivation, as compared with normal sleep, influences certain metabolic and cognitive parameters, related to food intake, hunger and memory functions, when participants are shielded from external time cues.

Official title: Metabolic and Cognitive Effects of Sleep Deprivation

Key Details

Gender

MALE

Age Range

20 Years - 28 Years

Study Type

INTERVENTIONAL

Enrollment

18

Start Date

2013-04

Completion Date

2014-09

Last Updated

2026-08-12

Healthy Volunteers

Yes

Interventions

BEHAVIORAL

Portion Size Task

Participants are given a computer program that gives them the opportunity to choose the portions of a variety of food items that they would ideally like to consume

PROCEDURE

Blood sample

In the morning following partial sleep deprivation or normal sleep, a blood sample will be taken to assess the level of metabolism-linked and neurodegenerative-linked molecules, as well as to assay blood serum and plasma for the presence of hormones involved in hunger such as ghrelin

PROCEDURE

Interference task

30-minute interference task

BEHAVIORAL

Memory tasks

Participants will be allowed to learn a procedural memory task before going to bed. Participants will be retested in the morning to assess their change in performance. Other memory tests will also be given to assess the working memory performance in the morning following the intervention.

BEHAVIORAL

Intake task

After a normal night of sleep or partial sleep deprivation, participants are presented with an ad libitum meal choice and can select the amount to ingest during a limited time window. Amount and selection will be recorded

BEHAVIORAL

Working memory function task

Participants will be evaluated on their working memory performance in the morning following either nighttime intervention (NS or PSD)

Locations (1)

Department of Neuroscience, Uppsala University

Uppsala, Uppsala County, Sweden