Clinical Research Directory

Inclusion Criteria: * Patient over 18 years, * Initial radiological diagnosis of venous or glomovenous vascular malformation proved by Doppler ultrasound and MRI, * Recurrence of symptoms after initial treatment, * Symptomatic deformation :pain, tangible mass,functional discomfort * Recurrence after treatment by surgery or sclerosis * Cryotherapy considered technically feasible after discussion in multidisciplinary committee, * Localization at distance from the skin and major neurovascular structures, * Absence of contra-indication of anaesthesia, * Signed informed consent, * Coverage by French social security Exclusion Criteria: * Localization of the lesion does not allow the implementation of cryotherapy in adequate conditions: ablation zone too close to the major anatomic structures (nerve), * TP \<50% TCA\> 1.5 x control, anticoagulation * Platelets \<90000/mm3, * Progressive infection * Patient included in another clinical study, * Unable to undergo medical tests for geographical, social or psychological, * Adult under a legal guardianship or unable to consent, * Pregnancy and breastfeeding.