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GLP-1 and Hypoglycemia
Sponsor: University of Maryland, Baltimore
Summary
Low blood sugar can negatively affect how blood vessels function, and this can lead to an increase in the risk for heart attacks, strokes and other problems related to the stiffening and blockage of blood vessels. The purpose of this study is to learn if and how glucagon-like peptide-1 (GLP-1; a naturally occurring hormone in the gut) changes the effects that low blood sugar levels have on blood vessels.
Official title: Hypoglycemia Associated Autonomic Dysfunction
Key Details
Gender
All
Age Range
18 Years - 45 Years
Study Type
INTERVENTIONAL
Enrollment
28
Start Date
2013-07
Completion Date
2026-12
Last Updated
2025-10-06
Healthy Volunteers
Yes
Conditions
Interventions
Glucagon-Like Peptide- 1 (GLP-1) infusion
GLP-1 infusion during experimental period
Placebo Comparator: Saline Infusion
Saline infusion (placebo) during experimental period
Locations (1)
University of Maryland, Baltimore
Baltimore, Maryland, United States