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The Neuro-protective Effects of Exercise in Children With Brain Tumors
Sponsor: The Hospital for Sick Children
Summary
The objectives of our proposed study are to (a) evaluate the feasibility of conducting a structured exercise program in children treated with cranial radiation for brain tumors, (b) test whether exercise results in improved thinking skills and emotional function, and (c) examine potential mechanisms of improved outcome, particularly recovery of white matter and grey matter.
Official title: The Neuro-protective Effects of Exercise in Children Treated With Cranial Radiation for Brain Tumors
Key Details
Gender
All
Age Range
7 Years - 17 Years
Study Type
INTERVENTIONAL
Enrollment
32
Start Date
2011-02-03
Completion Date
2015-03-16
Last Updated
2026-09-24
Healthy Volunteers
No
Conditions
Interventions
Exercise Program
Designed to improve cardio-respiratory fitness, the exercise program will be conducted for 12 weeks at a frequency of 3-4 sessions per week. Each exercise session will be conducted after school for a total duration of 90 minutes (group sessions) or 30 minutes (home-based sessions). Group session activities will include i) warm-up (i.e. walk/jog, games) \[10 mins\], ii) aerobic training/fitness games \[30 mins\], iii) organized sports \[30 mins\], iv) cool down (i.e. stretching, low intensity games) \[10 mins\] and v) snack and reward (15 mins). Participants in the Group setting had three 90-minute group sessions per week. Participants in the Combined setting had two 90-minute group sessions and two 30-minute individual home-based sessions per week.
Locations (1)
The Hospital for Sick Children
Toronto, Ontario, Canada