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Defining the Basis of Fibromuscular Dysplasia (FMD)
Sponsor: Icahn School of Medicine at Mount Sinai
Summary
The purpose of this study has evolved and expanded since its inception. Originally the intent was to establish the functional, molecular and genetic profile of fibroblasts from Fibromuscular Dysplasia (FMD) patients as compared to carefully matched control subjects. While this remains among the objectives, the study has been expanded to undertake a fully powered cross-tissue systems genetics analysis of FMD, and now also the related arteriopathies spontaneous coronary artery dissection (SCAD) and cervical artery dissection (CvAD). The overall objective is to disclose the core biologic mechanisms of these disorders.
Official title: Defining the Basis of Fibromuscular Dysplasia: The Define-FMD Study
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
600
Start Date
2013-10
Completion Date
2030-12
Last Updated
2025-09-29
Healthy Volunteers
Yes
Locations (1)
Icahn School of Medicine at Mount Sinai
New York, New York, United States