Clinical Research Directory

Inclusion Criteria: 1. Moms age 14 and older (will sign Informed Consent Statement (ICS), not an assent) 2. Mother of child enrolled must have a physician diagnosis of asthma or being treated for asthma (for 140 subjects; 40 subjects will be recruited from mothers and fathers without atopy - asthma, eczema, seasonal allergies) 3. Child must be enrolled during first week of life 4. Signed informed consent from parent(s) or legal guardian(s) Exclusion Criteria: 1. Child has a history of wheezing or underlying lung disease 2. Respiratory complications at birth (airway support higher then nasal cannula) 3. Born earlier then 37 weeks gestation 4. Congenital heart defects (not including Patent Ductus Arteriosus (PDA), hemodynamically insignificant Ventricular Septal Defect (VSD) or Atrial Septal Defect (ASD) 5. Underlying neuromuscular disease 6. Severe upper airway obstruction, sleep apnea, tracheomalacia, or laryngomalacia 7. Hydrocephalus 8. History of seizures 9. History of arrhythmia and baseline oxygenation level \<90% on room air 10. Infant is non-viable 11. Severe gastroesophageal reflux 12. Prior chest surgery or structural abnormalities of the lungs or chest wall 13. Has a history of adverse reaction to chloral hydrate 14. Ward of the state 15. Any physical finding(s) that would compromise the safety of the subject or the quality of the study data as determined by the site investigator