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Relationship Between Sperm Head Vacuoles and Sperm DNA Alterations in Infertile Men
Sponsor: University Hospital, Rouen
Summary
In men presenting sperm alterations, the selection of genetically undamaged spermatozoa need to be improved in order to increase the success of assisted reproduction treatments. The aim of this study is to determine whether the presence of sperm head vacuoles is associated with sperm DNA alterations.
Official title: Are Sperm Head Vacuoles Associated With Sperm Nuclear Alterations?
Key Details
Gender
MALE
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
200
Start Date
2013-12
Completion Date
2017-01
Last Updated
2026-06-10
Healthy Volunteers
Yes
Conditions
Interventions
Sperm Samples
The study will focus on sperm samples collected via masturbation for routine pre-IVF screening tests, taken from patients with isolated teratozoospermia or oligoasthenozoospermia. The various tests and analyses planned will be carried out on sperm not used for IVF or diagnostic purposes.
Locations (2)
Laboratoire de spermiologie, Hôpital Calmette, CHRU de Lille
Lille, France
Laboratoire de Biologie de la Reproduction - CECOS - EA 4308, CHU - Hôpitaux de Rouen
Rouen, France