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Local 5-Fluorouracil Injection for the Treatment of Chalazia: A Prospective, Comparative Study
Sponsor: University of Washington
Summary
Local injection of 5-fluorouracil into a chalazion (stye) is as effective as local injection of triamcinolone (steroid) and incision and curettage for treatment of chalazia.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
120
Start Date
2013-12
Completion Date
2026-07
Last Updated
2020-02-06
Healthy Volunteers
No
Conditions
Interventions
5-fluorouracil Injection
If the chalazion is present at follow-up visit, another injection of 5-FU will be given.
Triamcinolone Acetonide
If chalazion present at follow-up, another Triamcinolone injection will be done.
Incision and Curettage
If chalazion present at follow-up visit, patient will be randomized to receive local injection of either triamcinolone, 5-FU, or triamcinolone/5-FU mixture.
Triamcinolone Acetonide/5-fluorouracil mixture
If chalazion persists at follow-up visit, another injection of triamcinolone/5-FU mixture will be done.
Locations (1)
University of Washington Eye Institute at Harborview
Seattle, Washington, United States