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Comprehensive Pain Programme to Determine Mechanism of Transition of Acute to Chronic Postsurgical Pain
Sponsor: KK Women's and Children's Hospital
Summary
To determine whether central sensitization is a mechanism of CPSP (chronic postsurgical pain) in women who will develop CPSP compared to women with no CPSP after hysterectomy. This mechanism is illustrated by a higher pain score in experimental pain models such as tonic heat stimulation, increased evoked mechanical temporal summation and increased wound hyperalgesia.
Official title: Comprehensive Pain Programme to Determine Mechanism of Transition of Acute to Chronic Postsurgical Pain- Functional Brain Imaging, Quantitative Sensory Testing, Psychological and Genetic Screening: Prospective Cohort Study
Key Details
Gender
FEMALE
Age Range
21 Years - 70 Years
Study Type
INTERVENTIONAL
Enrollment
216
Start Date
2013-09
Completion Date
2017-06
Last Updated
2026-08-06
Healthy Volunteers
No
Interventions
pain testing
physical testing, psychological testing, genetics testing and functional brain imaging
Locations (1)
KK Women's and Children's Hospital
Singapore, Singapore