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ACTIVE NOT RECRUITING
NCT02044172
NA

Prostate Testing for Cancer and Treatment

Sponsor: University of Oxford

View on ClinicalTrials.gov

Summary

RATIONALE: Radical prostatectomy is surgery to remove the entire prostate. Radiation therapy uses high-energy x-rays or other types of radiation to kill tumor cells. Sometimes the tumor may not need treatment until it progresses. In this case, active surveillance may be sufficient. It is not yet known which treatment regimen is more effective for localized prostate cancer. PURPOSE: This randomized phase III trial is studying active monitoring to see how well it works compared with radical prostatectomy or radiation therapy in treating patients with localized prostate cancer.

Official title: The ProtecT Trial - Evaluating the Effectiveness of Treatments for Clinically Localised Prostate Cancer

Key Details

Gender

MALE

Age Range

50 Years - 69 Years

Study Type

INTERVENTIONAL

Enrollment

82849

Start Date

2001-06-01

Completion Date

2027-03-31

Last Updated

2022-11-14

Healthy Volunteers

Yes

Conditions

Interventions

PROCEDURE

Radical prostatectomy

radical prostatectomy

RADIATION

Conformal radiation therapy

Conformal radiation therapy, external beam

OTHER

Active monitoring

Active monitoring of Prostate specific antigen levels and disease surveillance

Locations (8)

Queen Elizabeth Hospital

Birmingham, United Kingdom

Southmead Hospital

Bristol, United Kingdom

Addenbrokes' Hospital

Cambridge, United Kingdom

University Hospital of Wales

Cardiff, United Kingdom

Western General Hospital

Edinburgh, United Kingdom

Leicester General Hospital

Leicester, United Kingdom

Freeman Hospital

Newcastle, United Kingdom

Royal Hallamshire Hospital

Sheffield, United Kingdom