Clinical Research Directory

Inclusion Criteria: * 2010 criteria for Rheumatoid Arthritis * Swelling of at least one joint and or elevated acute phase reactants * Greater than or equal to 40 years old or less than or equal to 65 year old female sex * cyclic citrullinated peptide antibody + in the past 12 months Exclusion Criteria: * hemoglobin \< 9 * white blood cell count \< 3.5 * Diagnosis of any active malignancy within the last 3 years besides non-melanomatous skin cancer * Diagnosis of diabetes and requires insulin * HIV+, Hep B S Ag+, Hep C polymerase chain reaction + * Untreated latent tuberculosis * Diagnosis of any additional systemic autoimmune connective tissue disease * Inability to reliably complete study requirements * History, physical, social or laboratory findings suggestive of any other medical or psychological condition that would, in the opinion of the principal investigator, make the candidate ineligible for the study