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Very Early veRsus Deferred Invasive Evaluation Using Computerized Tomography in Patients With Acute Coronary Syndromes
Sponsor: Rigshospitalet, Denmark
Summary
The aim of this study is to evaluate if acute invasive coronary evaluation and treatment conducted within 12 hours of diagnosis improves clinical outcome compared to a deferred, subacute strategy in patients with unstable angina pectoris (UAP) / non-ST segment elevation myocardial infarction (NSTEMI) Acute coronary syndrome (ACS) Furthermore, in an observational design the potential clinical benefit of coronary computed tomography angiography (CCTA) to select patients for invasive investigation and treatment in the two treatment arms (acute vs deferred) is evaluated. The following main hypothesis will be tested: * Very early invasive coronary investigation improves clinical outcome in patients with UAP/NSTEMI-ACS * CCTA performed before invasive coronary investigation will improve clinical management of patients with UAP/NSTEMI-ACS
Official title: Entire Danish Initiative To ImrpOve Revascularization Strategies (EDITORS) - A Randomised Evaluation of Clinical Outcome After Acute or Deferred Invasive Intervention Integrated With MDCT Imaging in Patients With Acute Coronary Syndromes
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
2500
Start Date
2010-11
Completion Date
2030-05
Last Updated
2022-12-12
Healthy Volunteers
No
Conditions
Interventions
Invasive coronary evaluation (Deferred)
Invasive coronary angiography and revascularization (PCI/CABG)
Invasive coronary evaluation (Acute)
Invasive coronary angiography and revascularization (PCI/CABG)
Locations (1)
Department of Cardiology and Radiology, Rigshospitalet, The Heart Center, Capital Region of Copenhagen, University of Copenhagen
Copenhagen, Denmark