Clinical Research Directory

Inclusion Criteria: * Age \> 18 years, * Primary or recurrent bladder tumor with endoscopic papillary aspect, * One or two bladder tumors, * Cytology before RTUV showing no high-grade cells, * Patients without tutorship or subordination (ou curatorship), * Patients under the general social security system or qualifying through a third party, * Informed consent signed by the patient after clear and fair information. Exclusion Criteria: * Age \< 18 years, * Allergy to mitomycin C, * Traumatic stenting, * Upper tract urothelial cancer, * Urethral invasion, * History of muscle invasive bladder cancer, * Extensive tumor (3 cm or more), * Any contraindication to RTUV, * Simultaneous participation in another clinical research study, * Patients not insured by the social security or not qualifying through a third party, * Patients with enhanced protection, namely pregnant or lactating women, persons deprived of their liberty by a judicial or administrative decision, people staying in a health or social institution, adults under legal protection, and finally patients in emergency situations, * Pregnant or lactating females or women of childbearing potential not willing to use an adequate method of birth control for the duration of the study (i.e. hormonal / mechanical contraceptive : oral, injectable, transdermal, implantable, intrauterine or surgical device: tubal ligation, hysterectomy, total oophorectomy).