Clinical Research Directory
Browse clinical research sites, groups, and studies.
Cerebral Metabolism in Patients With Refractory Chronic Cluster Headache Treated by Occipital Nerve Stimulation
Sponsor: Centre Hospitalier Universitaire de Nice
Summary
The occipital nerve stimulation (ONS) is used to treat patients with refractory primary chronic headache but its mechanism of action (MoA) remains unknown. Different hypothesis have been suggested in particular a specific action on cerebral generators involved in different types of primary headaches or a non specific action on pain modulatory network. The aim of this study, using the chronic cluster headache as a model, is to determine the changes in cerebral metabolism induced by ONS to precise its MoA in the treatment of primary chronic headache.
Official title: Study of the Cerebral Metabolism in Patients With Refractory Chronic Cluster Headache Treated by Occipital Nerve Stimulation
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
20
Start Date
2014-03-14
Completion Date
2022-02-02
Last Updated
2026-06-16
Healthy Volunteers
No
Conditions
Interventions
18F-FDG PET
Locations (4)
CHU -Hôpital Gabriel Montpied
Clermont-Ferrand, France
Institut des Neurosciences
Marseille, France
Département d'Evaluation et Traitement de la Douleur - Pôle Neurosciences Cliniques - Centre Hospitalo-Universitaire de Nice
Nice, France
Centre d'Urgence Céphalées
Paris, France