Clinical Research Directory

Inclusion Criteria (Experimental Group): * Stroke patients with persistent upper extremity (UE) deficits Inclusion Criteria (Control Group 1) * Stroke patients without UE impairments * Participants with risk factors for stroke * healthy controls * No known neurologic, psychiatric or developmental disability Inclusion Criteria (Control Group 2) * Stroke patients with persistent upper extremity (UE) deficits * Moderate upper extremity (dominant right hand affected) impairment (score of 1 or 2 on the motor sub-component of the NIH stroke scale (NIHSS) and ARAT score 20-45) * No upper extremity injury or conditions that limited use prior to the stroke * Pre-stroke independence with a Modified Rankin Score of 0 or 1, for the standard FES only intervention. Exclusion Criteria (for all participants): * Allergic to electrode gel, surgical tape and metals * Participants under treatment for infectious diseases or having apparent oral lesions or inflammation will be excluded from the study * Women who are pregnant or may become pregnant during the course of the study will be excluded * Participants with contraindications for MRI will be offered the opportunity to participate in the interventions study only (e.g. EEG-BCI-FES and behavioral testing) Exclusion Criteria (for healthy controls) * Contraindications for MRI * Allergic to electrode gel, surgical tape, and metals.