Clinical Research Directory
Browse clinical research sites, groups, and studies.
Locally Advanced Rectal Cancer - Exfoliated Peritoneal Tumor Cells
Sponsor: Oslo University Hospital
Summary
During the course of tumor growth and possibly by manipulation during the surgical procedure, cells from rectal tumors may be shed into the peritoneal cavity. Such cells may give rise to local recurrence or contribute to the formation of metastatic disease, specifically in the form of peritoneal carcinomatosis. Detection of cancer cells in the peritoneal cavity at the time of surgery might therefore be of value for prediction of disease recurrence with subsequent prognostic implications for these patients. In this study the investigators aim to determine the presence of exfoliated tumor cells in peritoneal lavage samples from patients undergoing surgery for LARC.
Official title: Prospective Observational Study of Exfoliated Peritoneal Tumor Cells in Locally Advanced Rectal Cancer
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
231
Start Date
2012-09
Completion Date
2028-01
Last Updated
2021-07-28
Healthy Volunteers
No
Conditions
Interventions
Observational study.
Biobanking of tissue (tumor biopsy, peritoneal lavage, blood specimen) from patients with locally advanced rectum cancer undergoing surgical resection of the primary tumor at the Norwegian Radium Hospital.
Locations (1)
The Norwegain Radium Hospital
Oslo, Ullern, Norway