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TERMINATED
NCT02114528
PHASE4

Anti-arrhythmic Therapy vs Catheter Ablation as First Line Treatment for AICD Shock Prevention

Sponsor: Ottawa Heart Institute Research Corporation

View on ClinicalTrials.gov

Summary

The purpose of this study is to determine whether catheter based ablation is better than conventional anti-arrhythmic drug (AAD) therapy for reducing recurrent shocks in patients with an implantable cardioverter defibrillator (ICD). The second purpose of the study is to determine the safety of catheter-based ablation and the effect on quality of life of patients. The study hypothesis is that catheter ablation is superior to AAD therapy in preventing recurrent ventricular arrhythmia in such subjects. This is a pilot trial which will provide data regarding recruitment potential and the feasibility of conducting a larger trial.

Official title: Antiarrhythmic Therapy Versus Catheter Ablation as First Line Treatment for AICD Shock Prevention: A Randomized Vanguard Pilot Trial

Key Details

Gender

All

Age Range

18 Years - 85 Years

Study Type

INTERVENTIONAL

Enrollment

3

Start Date

2014-10

Completion Date

2015-11

Last Updated

2026-05-04

Healthy Volunteers

No

Interventions

DRUG

Antiarrhythmic Drug Therapy

Either one or more of the following antiarrhythmic drugs: sotalol, mexiletine, procainamide, or amiodarone.

PROCEDURE

Catheter ablation

Ventricular tachycardia catheter ablation.

Locations (1)

University of Ottawa Heart Institute

Ottawa, Ontario, Canada