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Anti-arrhythmic Therapy vs Catheter Ablation as First Line Treatment for AICD Shock Prevention
Sponsor: Ottawa Heart Institute Research Corporation
Summary
The purpose of this study is to determine whether catheter based ablation is better than conventional anti-arrhythmic drug (AAD) therapy for reducing recurrent shocks in patients with an implantable cardioverter defibrillator (ICD). The second purpose of the study is to determine the safety of catheter-based ablation and the effect on quality of life of patients. The study hypothesis is that catheter ablation is superior to AAD therapy in preventing recurrent ventricular arrhythmia in such subjects. This is a pilot trial which will provide data regarding recruitment potential and the feasibility of conducting a larger trial.
Official title: Antiarrhythmic Therapy Versus Catheter Ablation as First Line Treatment for AICD Shock Prevention: A Randomized Vanguard Pilot Trial
Key Details
Gender
All
Age Range
18 Years - 85 Years
Study Type
INTERVENTIONAL
Enrollment
3
Start Date
2014-10
Completion Date
2015-11
Last Updated
2026-05-04
Healthy Volunteers
No
Interventions
Antiarrhythmic Drug Therapy
Either one or more of the following antiarrhythmic drugs: sotalol, mexiletine, procainamide, or amiodarone.
Catheter ablation
Ventricular tachycardia catheter ablation.
Locations (1)
University of Ottawa Heart Institute
Ottawa, Ontario, Canada