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ACTIVE NOT RECRUITING
NCT02119689

Vascular Reparative Mechanism in Diabetes

Sponsor: University of Alabama at Birmingham

View on ClinicalTrials.gov

Summary

The purpose of this research study is to study blood stem cells in diabetic patients and normal patients. We would like to better understand if these cells, called endothelial precursor cells (EPCs), are not working as expected in people with diabetes. We would like to see if the function of these cells can predict the development of diabetic retinopathy. Diabetic retinopathy is an eye disease associated with diabetes in which the cells of the retina are damaged. It can cause blurred vision, vision loss, blindness or possible bleeding in the retina. Even with current treatments, the quality of life for people with diabetic retinopathy is much reduced.

Official title: Vascular Reparative Mechanism by ACE2/Ang-(1-7) in Diabetes

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

78

Start Date

2011-10-30

Completion Date

2026-12-31

Last Updated

2025-12-23

Healthy Volunteers

Yes

Interventions

OTHER

Diabetic Patients

measuring CD34 cell function in relation to diabetic retinopathy status

OTHER

Healthy Controls

measuring CD34 cell function

Locations (1)

University of Alabama

Birmingham, Alabama, United States