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Vascular Reparative Mechanism in Diabetes
Sponsor: University of Alabama at Birmingham
Summary
The purpose of this research study is to study blood stem cells in diabetic patients and normal patients. We would like to better understand if these cells, called endothelial precursor cells (EPCs), are not working as expected in people with diabetes. We would like to see if the function of these cells can predict the development of diabetic retinopathy. Diabetic retinopathy is an eye disease associated with diabetes in which the cells of the retina are damaged. It can cause blurred vision, vision loss, blindness or possible bleeding in the retina. Even with current treatments, the quality of life for people with diabetic retinopathy is much reduced.
Official title: Vascular Reparative Mechanism by ACE2/Ang-(1-7) in Diabetes
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
78
Start Date
2011-10-30
Completion Date
2026-12-31
Last Updated
2025-12-23
Healthy Volunteers
Yes
Conditions
Interventions
Diabetic Patients
measuring CD34 cell function in relation to diabetic retinopathy status
Healthy Controls
measuring CD34 cell function
Locations (1)
University of Alabama
Birmingham, Alabama, United States