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Stool Transplants to Treat Refractory Clostridium Difficile Colitis
Sponsor: Duke University
Summary
It has been shown that restoration of the normal makeup of the bowel bacterial population is the most effective way to treat recurrent colitis due to Clostridium difficile. Restoration of the normal bowel bacterial population is best done by transplanting stool from a healthy donor. The investigators wish to transplant stool from healthy donors to treat recurrent C. difficile colitis by incorporating the stool into capsules that are administered by the oral route.
Official title: Fecal Microbiota Transplantation in Refractory Clostridium Difficile Colitis
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
77
Start Date
2016-04
Completion Date
2026-05
Last Updated
2025-08-13
Healthy Volunteers
No
Conditions
Interventions
fecal microbiota
fecal microbiota in capsule form
Locations (1)
Duke University Medical Center
Durham, North Carolina, United States