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ACTIVE NOT RECRUITING
NCT02128555
NA

Total Ankle Replacement Versus Arthrodesis Trial

Sponsor: University College, London

View on ClinicalTrials.gov

Summary

The purpose of TARVA is to determine whether Total Ankle Replacement (TAR) provides better clinical outcomes than ankle arthrodesis in patients aged 50-85 years with end-stage ankle osteoarthritis, and compare cost-effectiveness of the two treatments

Official title: A Randomised, Multi-centre, Non-blinded, Prospective, Parallel Group Trial of Total Ankle Replacement (TAR) Versus Ankle Arthrodesis in Patients With End Stage Ankle Osteoarthritis, Comparing Clinical Outcomes and Cost-effectiveness.

Key Details

Gender

All

Age Range

50 Years - 85 Years

Study Type

INTERVENTIONAL

Enrollment

303

Start Date

2015-01

Completion Date

2029-02-28

Last Updated

2021-03-15

Healthy Volunteers

Yes

Conditions

Interventions

PROCEDURE

Total Ankle Replacement

The joints are resurfaced with metal implants and a mobile plastic liner is placed between them as the gliding surface.

PROCEDURE

Arthrodesis

The remaining damaged cartilage is removed from the ends of the bone and the two bones are then held together in compression using screws, or plates until they join to become one (bone fusion), so that there is no longer any movement at that joint.

Locations (17)

Royal Cornwall Hospitals NHS Trust

Truro, Cornwall, United Kingdom

Brighton & Sussex University Hospitals NHS Trust

Brighton, United Kingdom

North Bristol NHS Trust

Bristol, United Kingdom

Cardiff and Vale Orthopaedic Centre

Cardiff, United Kingdom

Royal Derby Hospital

Derby, United Kingdom

Royal Surrey County Hospital

Guildford, United Kingdom

Hull and East Yorkshire Hospitals NHS Trust

Hull, United Kingdom

Aintree University Hospital

Liverpool, United Kingdom

Freeman Hospital

Newcastle, United Kingdom

Northumbria Healthcare NHS Foundation Trust

Newcastle, United Kingdom

Norfolk and Norwich University Hospitals NHS Foundation Trust

Norwich, United Kingdom

Nottingham University Hospitals NHS Trust

Nottingham, United Kingdom

Robert Jones & Agnes Hunt Orthopaedic Hospital

Oswestry, United Kingdom

Oxford University Hospitals NHS Foundation Trust

Oxford, United Kingdom

Northern General Hospital

Sheffield, United Kingdom

Royal National Orthopaedic Hospital NHS Trust

Stanmore, United Kingdom

Wrightington Hospital

Wigan, United Kingdom