Clinical Research Directory
Browse clinical research sites, groups, and studies.
Mechanisms and Factors Responsible for the Inhibition of Transposons During Fetal Gonad Development in Humans
Sponsor: Centre Hospitalier Universitaire Dijon
Summary
This is a single-centre study over 36 months for the inclusion of 30 patients. The selection and inclusion of patients will take place according to the criterion of Medical Termination of Pregnancy at 4 different gestational ages (8-12 weeks of gestation (WG)), 13-16 WG, 17-23 WG and 25-35 WG. The tissue analysed will principally be the gonads, other somatic tissue will also be systematically harvested in parallel (liver and psoas muscle) for control purposes. The gonads will be subjected to molecular biology analyses destined to quantify the expression of transposons and their inhibitors.
Key Details
Gender
MALE
Age Range
10 Weeks - 37 Weeks
Study Type
OBSERVATIONAL
Enrollment
30
Start Date
2014-01-29
Completion Date
2027-01
Last Updated
2022-07-08
Healthy Volunteers
No
Interventions
surgical biopsies
Locations (1)
CHU de DIJON
Dijon, France