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ACTIVE NOT RECRUITING
NCT02191488
PHASE1

ALA-induced PpIX Fluorescence During Brain Tumor Resection

Sponsor: David W. Roberts

View on ClinicalTrials.gov

Summary

Removing a tumor from a patients brain is hard to do because, very often, brain tumors do not have boundaries that are easy for the patients surgeon to find. In many cases, the surgeon can't tell exactly where the tumor begins or ends. The surgeon usually can remove most of the patient's tumor by looking at the MRI images that were taken of the patient's brain before surgery. However, the surgeon does not have any good way to tell if the entire tumor has been removed or not. Removing the entire tumor is very important because leaving tumor behind may allow it to grow back which could decrease the chances of survival.

Official title: Quantification of ALA-induced PpIX Fluorescence During Brain Tumor Resection

Key Details

Gender

All

Age Range

21 Years - Any

Study Type

INTERVENTIONAL

Enrollment

540

Start Date

2014-07

Completion Date

2026-12-31

Last Updated

2025-09-15

Healthy Volunteers

No

Conditions

Interventions

DRUG

5-aminolevulinic acid

Locations (1)

Dartmouth-Hitchcock Medical Center

Lebanon, New Hampshire, United States