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Screening for Synchronous Metastases in Colorectal Cancer With DW-MRI (SERENADE)
Sponsor: Imperial College London
Summary
Eligible patients with high risk colorectal malignancy (T3/4, spread greater than 5mm, EMVI positive) will have additional surveillance of breath hold T1, T2 and DW-MRIs (no IV contrast) post surgery six monthly for three years. Findings of liver MRIs as reported by radiology PI will be shared with their local MDT who make decisions as appropriate, including the management of any identified liver metastases, according to local protocol.
Official title: Screening for Synchronous Metastases in Colorectal Cancer With DW-MRI.
Key Details
Gender
All
Age Range
16 Years - Any
Study Type
INTERVENTIONAL
Enrollment
282
Start Date
2014-08
Completion Date
2031-12
Last Updated
2024-10-17
Healthy Volunteers
No
Interventions
Diffusion Weighted MRI scan
Liver metastases found on the additional DW-MRI scans will be discussed at MDT and treated according to local site policy.
Locations (13)
Macclesfield District General Hospital
Macclesfield, Cheshire, United Kingdom
Queen's Hospital
Burton-on-Trent, Derbyshire, United Kingdom
Broomfield Hospital
Chelmsford, Essex, United Kingdom
Royal Bolton Hospital
Bolton, Greater Manchester, United Kingdom
Medway Maritime Hospital
Gillingham, Kent, United Kingdom
University Hospital of South Manchester & Manchester Royal Infirmary
Wythenshawe, Manchester, United Kingdom
Royal Liverpool Hospital
Liverpool, Merseyside, United Kingdom
Royal Stoke University Hospital
Stoke-on-Trent, Staffordshire, United Kingdom
Royal Marsden Hospital
Sutton, Surrey, United Kingdom
Royal Gwent Hospital
Newport, Wales, United Kingdom
George Eliot Hospital
Nuneaton, Warwickshire, United Kingdom
Salisbury District Hospital
Salisbury, Wiltshire, United Kingdom
Queen Alexandra Hospital
Portsmouth, United Kingdom