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ACTIVE NOT RECRUITING
NCT02278601
PHASE3

Comparison of Regimens MPIB, CIPCEA, PCEA

Sponsor: KK Women's and Children's Hospital

View on ClinicalTrials.gov

Summary

Epidural analgesia is the gold standard of pain relief for labour pain. Despite this, more than 50% of parturients continue to experience pain leading to suffering and increased caregiver workload. Women who have increased pain tend to have lower successful patient bolus demands when patient controlled epidural analgesia (PCEA) is utilised and have dysfunctional labour requiring obstetric intervention such as Caesarean or instrumental delivery. Labour pain often escalates and worsens as labour progresses requiring an individualized, variable, flexible analgesic regimen. Bolus epidural administrations have been shown to improve uniform spread of local anaesthetics with better pain relief, compared to fixed background infusions.

Official title: Comparison of Modified Programmed Intermittent Bolus (MPIB), Computer-integrated Patient Controlled Epidural Analgesia (CIPCEA) and Conventional Patient Controlled Epidural Analgesia (PCEA) During Labour

Key Details

Gender

FEMALE

Age Range

21 Years - 50 Years

Study Type

INTERVENTIONAL

Enrollment

839

Start Date

2015-01-28

Completion Date

2026-12-31

Last Updated

2024-10-09

Healthy Volunteers

No

Interventions

DEVICE

epidural delivery system

epidural delivery system for maintenance of labour epidural analgesia using 0.1% ropivacaine (amide local anaesthetic) with 2mcg/ml fentanyl (opioid) as maintenance solution

DRUG

Ropivacaine

epidural delivery system for maintenance of labour epidural analgesia using 0.1% ropivacaine (amide local anaesthetic) with 2mcg/ml fentanyl (opioid) as maintenance solution

DRUG

Fentanyl

epidural delivery system for maintenance of labour epidural analgesia using 0.1% ropivacaine (amide local anaesthetic) with 2mcg/ml fentanyl (opioid) as maintenance solution

Locations (1)

KK Women's and Children's Hospital

Singapore, Singapore