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RECRUITING
NCT02351141
NA

Structure and Function MRI of Asthma

Sponsor: Dr. Grace Parraga

View on ClinicalTrials.gov

Summary

The investigators will apply 129Xenon and/or 3He image acquisition and analysis methods in 200 asthma patient volunteers in order to characterize and probe the relationship between lung structure and function using imaging.

Key Details

Gender

All

Age Range

18 Years - 60 Years

Study Type

INTERVENTIONAL

Enrollment

200

Start Date

2015-01

Completion Date

2028-12

Last Updated

2025-08-11

Healthy Volunteers

No

Conditions

Interventions

OTHER

Hyperpolarized Noble Gas MRI

Hyperpolarized Helium-3 and/or Xenon-129. Noble gas magnetic resonance imaging (MRI) has recently emerged as another research approach for the non-invasive measurement of lung structure and function, including conduction of gas through airways and into airspaces. Noble gas MRI provides a complimentary and alternative method for evaluating lung disease and may be superior to CT because it allows simultaneous visualization of both airway and airspace structure and function.

Locations (1)

Robarts Research Institute; The University of Western Ontario; London Health Sciences Centre

London, Ontario, Canada