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Structure and Function MRI of Asthma
Sponsor: Dr. Grace Parraga
Summary
The investigators will apply 129Xenon and/or 3He image acquisition and analysis methods in 200 asthma patient volunteers in order to characterize and probe the relationship between lung structure and function using imaging.
Key Details
Gender
All
Age Range
18 Years - 60 Years
Study Type
INTERVENTIONAL
Enrollment
200
Start Date
2015-01
Completion Date
2028-12
Last Updated
2025-08-11
Healthy Volunteers
No
Conditions
Interventions
Hyperpolarized Noble Gas MRI
Hyperpolarized Helium-3 and/or Xenon-129. Noble gas magnetic resonance imaging (MRI) has recently emerged as another research approach for the non-invasive measurement of lung structure and function, including conduction of gas through airways and into airspaces. Noble gas MRI provides a complimentary and alternative method for evaluating lung disease and may be superior to CT because it allows simultaneous visualization of both airway and airspace structure and function.
Locations (1)
Robarts Research Institute; The University of Western Ontario; London Health Sciences Centre
London, Ontario, Canada