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Impairment of Central Coherence in Restrictive Anorexia Nervosa (CoCA)
Sponsor: Nantes University Hospital
Summary
The current etiological pathological model of anorexia nervosa is poly-factorial involving individual genetic and psychological factors, in close interaction with environmental, family and socio-cultural factors. Among these factors, this study focuses on the central coherence process (cognitive ability to integrate complex information into a comprehensive meaning), in the active phase of the disease. Therefore, patients followed in the addiction service of the Nantes University Hospital will perform neuropsychological tests assessing executive functions involved in the process of central coherence. Impairment of central coherence process could act as a maintenance factor of the disease, particularly in connection with body dysmorphic disorder. The therapeutic perspectives acting on the central coherence process like cognitive remediation deserve to deepen knowledge on the cognitive profile of patients with anorexia nervosa.
Official title: Impairment of Central Coherence in Restrictive Anorexia Nervosa: Single-center and Case-control Study
Key Details
Gender
FEMALE
Age Range
15 Years - Any
Study Type
INTERVENTIONAL
Enrollment
122
Start Date
2015-06-11
Completion Date
2017-08-16
Last Updated
2026-09-14
Healthy Volunteers
Yes
Conditions
Interventions
One interview of 90 minutes with a part of cognitive assessment and a part of self-assessment
The content of the assessment will be the same for all subjects and will consist of a part of cognitive assessment (National Reading Test, Rey Osterreich Complex Figure, Hayling Sentence Completion Task, verbal memory, digit sequencing, token motor task, verbal fluencies, symbol coding, tower of London) and self-assessment (Mini International Neuropsychiatric Interview, Beck Depression Inventory, State Trait Anxiety Inventory, Wender Utah Rating Scale, Adult Self-Report Scale Symptom Checklist, UPPS Impulsive Behavior Scale)
Locations (1)
CHU de Nantes, Service d'Addictologie
Nantes, France