Clinical Research Directory

Inclusion Criteria: * All patients must have histologic proof of solid tumor malignancy and radiographic evidence of spine metastasis * Eastern Cooperative Oncology Group (ECOG) performance status =\< 2 (Karnofsky \>= 60%) * Life expectancy of greater than 3 months * All patients must be able to lie supine * All patients must have no more than 3 contiguous vertebral body levels treated at a single site, and no more than 3 discontiguous vertebral body levels treated * All patients must have a single fraction spine radiosurgery at the designated site of interest to at least a dose of 18 Gray (Gy) * All patients must be deemed at "high risk" of developing vertebral body fracture by having at least one of the following characteristics: * Spine Instability Neoplastic Score classification of "Indeterminate" deemed as a score from 7 to 12 * Pre-existing vertebral body fracture * Planned radiation dose of 24 Gy * All patients must have a vertebral body site to be treated located from T1 to L5 * Women of child-bearing potential and men must agree to use adequate contraception (hormonal or barrier method of birth control; abstinence) prior to study entry and for the duration of study participation; should a woman become pregnant or suspect she is pregnant while she or her partner is participating in this study, she should inform her treating physician immediately * All patients must sign informed consent verifying that they are aware of the investigational nature of this study in keeping with the rules and policies of M.D. Anderson Cancer Center; the only acceptable consent is the one approved by M.D. Anderson Institutional Review Board (IRB) * Patients undergoing bisphosphonate therapy are allowed Exclusion Criteria: * Patients who have had prior radiotherapy at the spine site and level to be treated * Patients who have had prior surgery at the spine level to be treated to include prior cement augmentation, laminectomy, vertebrectomy, tumor debulking, instrumentation * Patients with gross disease involving only the posterior elements * Patients who have \> 50% vertebral body collapse * Patients unable to undergo magnetic resonance imaging (MRI) of the spine * Patents with cord compression * Patients deemed not be a candidate for cement augmentation for any reason * Patients who have frank mechanical pain * Patients with both pedicles involved with gross disease at the level of potential cement augmentation * Pregnant women are excluded from this study * Patients with a histology of lymphoma, myeloma and small cell lung cancer histologies