Clinical Research Directory
Browse clinical research sites, groups, and studies.
Ethanol and Cannabinoid Effects on Simulated Driving and Related Cognition
Sponsor: Yale University
Summary
The overarching goal of this study is to characterize the effects of ethanol and cannabinoids on simulated driving and related cognition.
Key Details
Gender
All
Age Range
21 Years - 55 Years
Study Type
INTERVENTIONAL
Enrollment
40
Start Date
2015-12
Completion Date
2025-12
Last Updated
2025-04-15
Healthy Volunteers
Yes
Interventions
Active delta-9-THC
Low dose (0.015 mg/kg = 1.05 mg in a 70 kg individual) THC, dissolved in alcohol. This dose is roughly equivalent to smoking approximately 1/4 of a marijuana cigarette, or "joint". Administered over 20 minutes.
Placebo
Control: small amount of alcohol (quarter teaspoon), with no THC. Administered over 20 minutes.
Active Ethanol
Target BrAC of 0.04% reached over 20 minutes and then clamped to maintain this dose for an additional 60 minutes. This dose is equivalent to consuming approximately 2 drinks over 1 hour. Administered over a total of 80 minutes.
Placebo
Control: no alcohol, administered for a total of 80 minutes.
Locations (1)
Biological Studies Unit, VA Connecticut Healthcare System
West Haven, Connecticut, United States