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Lyme Borreliosis and Early Cutaneous Diagnostic
Sponsor: University Hospital, Strasbourg, France
Summary
Test and evaluate a new diagnostic method (SRM-MS/MS: Selected Reaction Monitoring- Mass spectrometry) for Lyme Borreliosis on human skin biopsies. Patients included are those with the early skin manifestation (erythema migrans). This new proteomic method will be compared to the two existing method: culture of Borrelia and PCR detection of Borrelia (DNA detection of the bacteria).
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
84
Start Date
2015-08-06
Completion Date
2024-02-01
Last Updated
2026-07-13
Healthy Volunteers
No
Conditions
Interventions
Skin biopsies
Skin biopsies of patients with Lyme disease (erythema migrans) infected with Borrelia burgdorferi sensu lato will be analyzed by three diagnostic techniques : molecular technique (PCR), biological technique (culture of the bacteria) and proteomics technique (SRM/ MS-MS)
Locations (7)
Centre Hospitalo-Universitaire Jean Minjoz
Besançon, France
Centre Hospitalier William Morey
Chalon-sur-Saône, France
Hôpital Pasteur
Colmar, France
Hôpital E. Muller
Mulhouse, France
Hôpital Robert Debré
Reims, France
Hôpitaux Universitaires de Strasbourg
Strasbourg, France
Hôpital Bel Air
Thionville, France