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Safety and Durability of Sirolimus for Treatment of LAM
Sponsor: University of Cincinnati
Summary
The MIDAS study aims to follow male and female LAM patients who are currently taking, have previously failed or been intolerant of, or may (at some time in the future) take mTOR inhibitors (sirolimus or everolimus) as part of their clinical care. Adult female TSC patients may also enroll, with or without lung cysts.
Official title: Multicenter International Durability and Safety of Sirolimus in LAM Trial (MIDAS)
Key Details
Gender
FEMALE
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
600
Start Date
2015-03
Completion Date
2025-07-31
Last Updated
2024-12-24
Healthy Volunteers
No
Conditions
Interventions
Sirolimus
Sirolimus treatment will be part of a participant's clinical care and will be managed by their physician.
Everolimus
Everolimus treatment will be part of a participant's clinical care and will be managed by their physician.
Locations (20)
Stanford University Medical Center
Stanford, California, United States
National Jewish Health
Denver, Colorado, United States
Mayo Clinic Jacksonville
Jacksonville, Florida, United States
Emory University School of Medicine
Atlanta, Georgia, United States
Loyola University Medical Center, Chicago
Maywood, Illinois, United States
Brigham and Women's Hospital
Boston, Massachusetts, United States
University of Michigan
Ann Arbor, Michigan, United States
Mayo Clinic Rochester
Rochester, Minnesota, United States
Washington University School of Medicine
St Louis, Missouri, United States
University of Rochester Medical Center
Rochester, New York, United States
University of Cincinnati
Cincinnati, Ohio, United States
Cleveland Clinic
Cleveland, Ohio, United States
Oregon Health and Science University
Portland, Oregon, United States
University of Pennsylvania Medical Center
Philadelphia, Pennsylvania, United States
Medical University of South Carolina
Charleston, South Carolina, United States
Vanderbilt University Medical Center
Nashville, Tennessee, United States
University of Texas Southwestern Medical Center
Dallas, Texas, United States
University of Texas Health Center
Houston, Texas, United States
University of Utah School of Medicine
Salt Lake City, Utah, United States
Swedish Medical Center
Seattle, Washington, United States