Clinical Research Directory
Browse clinical research sites, groups, and studies.
CHildhood ASthma and Environment Research Study - CHASER Study
Sponsor: Stefania La Grutta, MD
Summary
"CHildhood ASthma and Environment Research study - CHASER study" is an observational longitudinal study in outpatient clinic of Pediatric Allergology \& Pulmonology (PAP) of Respiratory Disease Research Center (RDRC) within the Institute of Biomedicine and Molecular Immunology (IBIM) of the National Research Council (CNR) of Palermo (RDRC-IBIM CNR), Italy. The first phase - transversal study will identify determinants of pediatric asthma control The second phase - longitudinal study, in patients with persistent asthma, will be focused on: * predictors for asthma exacerbations and loss of control * real life adherence to asthma therapy guidelines * phenotypic characterization through the collection of saliva samples * assessment of alterations and inflammatory changes in the nasal mucosa through nasal brushing * evaluation of the presence of 8-isoprostane, nicotine, cotinine and bisphenol-A through urine analysis. Chaser Project is expected to improve the knowledge of pediatric asthma in patients with different level of control, identifying predictors for asthma exacerbations and loss of control.
Key Details
Gender
All
Age Range
5 Years - 16 Years
Study Type
OBSERVATIONAL
Enrollment
2660
Start Date
2011-09
Completion Date
2020-02
Last Updated
2026-04-13
Healthy Volunteers
No
Conditions
Locations (1)
Institute of Biomedicine and Molecular Immunology, IBIM
Palermo, Palermo, Italy