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ACTIVE NOT RECRUITING
NCT02461459

Autism Spectrum Disorder (ASD) and Intellectual Disability (ID) Determinants in Tuberous Sclerosis Complex (TSC)

Sponsor: Boston Children's Hospital

View on ClinicalTrials.gov

Summary

The purpose of this study is to characterize the developmental phenotype of ASD and ID and to identify biomarkers using advanced MRI methodology and electrophysiological biomarkers of synaptic function and connectivity predictive of ASD and ID presence and severity in patients with TSC. In addition, this study will be establishing infrastructure for the collection and storage of human bio-specimens, including genetic material, from TSC patients and their family members with ASD.

Key Details

Gender

All

Age Range

18 Months - Any

Study Type

OBSERVATIONAL

Enrollment

205

Start Date

2015-05

Completion Date

2026-12

Last Updated

2024-10-26

Healthy Volunteers

Yes

Locations (6)

University of Alabama at Birmingham

Birmingham, Alabama, United States

University of California at Los Angeles

Los Angeles, California, United States

Stanford University

Palo Alto, California, United States

Boston Children's Hospital

Boston, Massachusetts, United States

Cincinnati Children's Hospital Medical Center

Cincinnati, Ohio, United States

University of Texas at Houston

Houston, Texas, United States