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Immune Function in Acute Kidney Injury
Sponsor: Guy's and St Thomas' NHS Foundation Trust
Summary
The immune response to kidney damage during acute kidney injury (AKI) is an important contributor to the prolonged lack of renal function and progression of kidney injury. Most data related to intrarenal and interorgan pathways in AKI stem from animal research with sometimes conflicting results. Accurate evaluation of these processes in humans and identification of early diagnostic tools are critical for the development of strategies to prevent and attenuate AKI-related morbidity and mortality in patients. The aim of this study is to evaluate immune function and miRNA expression in hospitalised patients with and without AKI.
Official title: Evaluation of Immune Function in Patients With Acute Kidney Injury
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
120
Start Date
2013-06
Completion Date
2026-12-01
Last Updated
2024-01-23
Healthy Volunteers
No
Conditions
Interventions
AKI
development of immune dysregulation and rise in inflammatory markers and activation of immune cells
Locations (1)
Guy's & St Thomas Foundation Hospital
London, United Kingdom