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Sodium Bicarbonate to Treat Severe Acidosis in the Critically Ill
Sponsor: University Hospital, Montpellier
Summary
The purpose of the present study is to compare the adjunct treatment of metabolic or mixed severe acidosis in the critically ill using Sodium Bicarbonate as a buffer to increase the plasma pH vs no buffering therapy. The study is a randomized multiple center clinical trial with the outcome as a primary endpoint.
Official title: Sodium Bicarbonate to Treat Severe Acidosis in the Critically Ill : A Multiple Center Randomized Clinical Trial (BICAR-ICU)
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
400
Start Date
2015-05-05
Completion Date
2017-05-29
Last Updated
2026-06-15
Healthy Volunteers
No
Conditions
Interventions
Sodium Bicarbonate
Intravenous 4.2% Sodium Bicarbonate 125ml to 250ml / 30min up to 1000ml/24h to maintain plasma pH equal or greater than 7.30
Locations (1)
DAR St Eloi
Montpellier, France