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Preliminary Evaluation of Screening for Pancreatic Cancer in Patients With Inherited Genetic Risk
Sponsor: Abramson Cancer Center at Penn Medicine
Summary
The study is a prospective, observational study evaluating the utility of endoscopic ultrasound or MRI for the identification of preneoplastic and neoplastic pancreatic lesions in patients at high risk for pancreatic cancer, specifically those with BRCA1/2, ATM, or PALB2 mutations.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
200
Start Date
2015-05
Completion Date
2030-05
Last Updated
2026-02-05
Healthy Volunteers
No
Conditions
Interventions
Collection of data from endoscopic ultrasound or MRI/MRCP of the abdomen
Participants in this study should be undergoing pancreatic cancer screening with endoscopic ultrasound or MRI as part of their standard care. These should typically be done at least every 12 months, and the imaging tests will be ordered as routine clinical tests and will be billed to the participant's insurance. This study does not cover the costs of these screening tests, however the study will track the results of these screening tests.
Blood sample collection for research
Up to 40mL of blood may be collected for analysis at each screening examination.
Locations (1)
Abramson Cancer Center of the University of Pennsylvania
Philadelphia, Pennsylvania, United States