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Effects of Epicatechin on Statins for Mitochondrial Dysfunction and Impaired Exercise Capacity
Sponsor: University of California, San Diego
Summary
The purpose of this study is to gain insight into the side-effects of statin consumption, and assess the ability of epicatechin (a compound in dark chocolate) to counteract or reverse these changes. The investigators' prior research has shown that epicatechin can improve skeletal muscle structure and mitochondrial (which gives us energy) structure.
Official title: Effects of Epicatechin on Patients With Statin-induced Mitochondrial Dysfunction and Impaired Exercise Capacity
Key Details
Gender
All
Age Range
30 Years - 75 Years
Study Type
INTERVENTIONAL
Enrollment
19
Start Date
2015-06
Completion Date
2021-07-28
Last Updated
2026-07-31
Healthy Volunteers
Yes
Conditions
Interventions
Pure epicatechin capsules (50mg)
Epicatechin is a compound found naturally in dark chocolate.
Simvastatin (40mg)
A cholesterol-lowering medication that blocks the production of cholesterol.
Placebo
A substance that has no therapeutic effect and will act as a control.
Locations (1)
University of California, San Diego
La Jolla, California, United States