Clinical Research Directory

Inclusion Criteria: * Affiliation to a health insurance * Patients candidates for bariatric surgery based on criteria established by international experts (BMI\> 40 or\> 35 kg / m² with severe comorbidities, after failure of multidisciplinary care for a period of at least 1 year) * Written consent after oral and written informations Exclusion Criteria: * Topic guardianship, curatorship or safeguard justice. * Taking a treatment known to alter the perception of taste * Oral Decay can affect the perception of taste * Treatment that may interfere with intestinal peptides or lipids receptors (especially DDP4 inhibitors, anti-inflammatory medications, intestinal lipase inhibitors: Xenical) * Tobacco use, alcohol or drugs abuse * Known coagulopathy, abnormal hemostasis tests or abnormal platelets count, treatment interfering with coagulation or platelet aggregation * Contraindication to bariatric surgery * Malignant pathology, severe liver disease or severe inflammatory disease, malabsorption. * Pregnancy * Positive serology for VIH, VBH and CVH