Clinical Research Directory

Inclusion Criteria: * Genetic diagnosis of Friedreich's ataxia by DNA sequencing, mutational analysis or protein assay OR be a healthy subject with no evidence of a neuromuscular disorder * Between the ages of 6 and 70 (inclusive) * Are able to tolerate metabolic exercise testing * Are stable on cardiac medication regimen for 3 months prior to screening Exclusion Criteria: * Presence of unstable heart disease * Receipt of cardiac transplant * Any concurrent medical condition which, in the opinion of the investigators, would make the subject unsuitable for the study