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Lipidomics, Proteomics, Micro RNAs and Volatile Organic Compounds (VOC)
Sponsor: AdventHealth
Summary
This is a non-randomized natural history protocol in which patients undergoing surgery or endoscopy for suspected/ diagnosed pancreaticobiliary strictures are assigned to a) control (chronic pancreatitis, no pancreatic neoplasm, primary sclerosing cholangitis), b) non-carcinoma (bile duct stones, papillary stenosis, ), c) carcinoma non-pancreatic (ampullary and distal bile duct or cholangiocarcinoma) and d) pancreatic ductal adenocarcinoma (pancreatic cancer.
Official title: Lipidomics, Proteomics, Micro RNAs and Volatile Organic Compounds Biomarkers in Bile and Serum in the Diagnosis of Malignant Biliary Strictures
Key Details
Gender
All
Age Range
19 Years - 95 Years
Study Type
OBSERVATIONAL
Enrollment
500
Start Date
2014-11-13
Completion Date
2026-12-01
Last Updated
2026-02-05
Healthy Volunteers
No
Conditions
Interventions
blood and bile
20ml of blood will be obtained from consented participants. 5ml of bile will be collected during the endoscopic procedure.
Locations (1)
AdventHealth
Orlando, Florida, United States