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Secondary Sclerosing Cholangitis in Critically Ill Patients
Sponsor: Medical University of Graz
Summary
SSC-CIP is increasing in patients after critical illness. Pathogenesis is still largely unclear. The investigators hypothesize that genetic variants of biliary transporter genes are frequent in patients with SSC-CIP. In approximately 140 patients and controls the rate of genetic variants in biliary transporter genes, gut permeability and gut microbiome as well as bone health will be studied.
Official title: Secondary Sclerosing Cholangitis in Critically Ill Patients (SSC-CIP): A Pilot Study on the Possible Genetic Basis of the Disease
Key Details
Gender
All
Age Range
18 Years - 99 Years
Study Type
OBSERVATIONAL
Enrollment
140
Start Date
2015-12-21
Completion Date
2028-01
Last Updated
2025-03-04
Healthy Volunteers
No
Conditions
Locations (1)
Department of Internal Medicine, Medical University of Graz
Graz, Austria