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Circulating Tumour DNA (ctDNA) in Patients With Colorectal Cancer and the Relationship to Imaging Features of Extramural Venous Invasion
Sponsor: Imperial College London
Summary
This study does not involve randomization or treatment. Eligible patients have colorectal adenocarcinoma with no metastases eligible for curative surgery. A pre operative staging scan must have been completed within 6 weeks prior to surgery. Two x 20ml blood samples will be taken from each patient, one prior to and one during or within 24hrs after surgery. Patients are annually followed up to 3 years.
Key Details
Gender
All
Age Range
16 Years - Any
Study Type
OBSERVATIONAL
Enrollment
100
Start Date
2015-11
Completion Date
2029-12
Last Updated
2024-10-17
Healthy Volunteers
No
Conditions
Interventions
Blood sample (mrEMVI positive patient)
Two blood samples are taken from each patient with mrEMVI positive tumours post chemoradiotherapy. One pre-surgery and one during surgery from a peripheral vein.
Blood sample (mrEMVI negative patient)
Locations (3)
Queen Elizabeth the Queen Mother Hospital
Margate, Kent, United Kingdom
St Mary's Hospital (Imperial)
Hammersmith, London, United Kingdom
Royal Marsden Hospital NHS Foundation Trust
Sutton, Surrey, United Kingdom