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Autologous Bone Marrow Aspirate Concentrate in Patients Undergoing Meniscectomy
Sponsor: Rush University Medical Center
Summary
The proposed research study aims to evaluate the effects of autologous bone marrow aspirate concentrate (BMAC) on the development and progression of osteoarthritis (OA) in patients undergoing meniscectomy. This prospective, randomized, double-blind clinical trial will compare patient-reported outcomes, specifically IKDC scores between patients who receive BMAC post-meniscectomy and those who receive a saline control injection. The study will also compare physical examination, MRI, radiographs, and synovial fluid analysis. Our hypothesis is that those who receive the autologous BMAC injection after the procedure will have better outcomes than those who do not.
Official title: Prospective, Randomized, Double-blind Clinical Trial to Investigate the Efficacy of Autologous Bone Marrow Aspirate Concentrate Post-Meniscectomy
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
100
Start Date
2017-12-22
Completion Date
2026-12-31
Last Updated
2025-03-28
Healthy Volunteers
No
Conditions
Interventions
Bone Marrow Aspirate Concentrate
Subjects undergoing autologous bone marrow aspirate concentrate will receive an intra-articular injection into the affected knee.
Standard Meniscectomy
All subjects will undergo either a partial or complete meniscectomy to treat the torn meniscus.
Locations (1)
Rush University Medical Center
Chicago, Illinois, United States