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RECRUITING
NCT02582489
NA

Autologous Bone Marrow Aspirate Concentrate in Patients Undergoing Meniscectomy

Sponsor: Rush University Medical Center

View on ClinicalTrials.gov

Summary

The proposed research study aims to evaluate the effects of autologous bone marrow aspirate concentrate (BMAC) on the development and progression of osteoarthritis (OA) in patients undergoing meniscectomy. This prospective, randomized, double-blind clinical trial will compare patient-reported outcomes, specifically IKDC scores between patients who receive BMAC post-meniscectomy and those who receive a saline control injection. The study will also compare physical examination, MRI, radiographs, and synovial fluid analysis. Our hypothesis is that those who receive the autologous BMAC injection after the procedure will have better outcomes than those who do not.

Official title: Prospective, Randomized, Double-blind Clinical Trial to Investigate the Efficacy of Autologous Bone Marrow Aspirate Concentrate Post-Meniscectomy

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

100

Start Date

2017-12-22

Completion Date

2026-12-31

Last Updated

2025-03-28

Healthy Volunteers

No

Interventions

BIOLOGICAL

Bone Marrow Aspirate Concentrate

Subjects undergoing autologous bone marrow aspirate concentrate will receive an intra-articular injection into the affected knee.

PROCEDURE

Standard Meniscectomy

All subjects will undergo either a partial or complete meniscectomy to treat the torn meniscus.

Locations (1)

Rush University Medical Center

Chicago, Illinois, United States