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Whole Exome Sequencing in Finding Causative Variants in Germline DNA Samples From Patients With Hypertension Receiving Bevacizumab for Breast Cancer
Sponsor: National Cancer Institute (NCI)
Summary
This research trial studies whole exome sequencing in finding causative variants in germline deoxyribonucleic acid (DNA) samples from patients with hypertension receiving bevacizumab for breast cancer. Studying samples of germline DNA in the laboratory from patients with hypertension receiving bevacizumab for breast cancer may help doctors learn about changes that occur in DNA and identify biomarkers related to hypertension.
Official title: Exploratory Next Generation Sequencing to Identify Causative Variants for Bevacizumab-Induced Hypertension From Breast Cancer Study E5103 Germline DNA Samples
Key Details
Gender
All
Age Range
Any - Any
Study Type
OBSERVATIONAL
Enrollment
354
Start Date
2014-03-25
Completion Date
2100-01-01
Last Updated
2026-03-27
Healthy Volunteers
No
Conditions
Interventions
Laboratory Biomarker Analysis
Correlative studies
Locations (1)
Eastern Cooperative Oncology Group
Boston, Massachusetts, United States